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Aim

Theory

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Procedure

Simulation

Posttest

References

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Determination of True Density of a Pharmaceutical Powder Sample using Solvent Displacement Method

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1. True density of a powder is defined as:

a: Mass of powder per unit apparent volume Explanation

Explanation

b: Mass of powder per unit true volume excluding void spaces Explanation

Explanation

c: Weight of powder per bulk volume Explanation

Explanation

d: Ratio of volume to surface area Explanation

Explanation

2. The instrument commonly used in solvent displacement method is:

a: Pycnometer or specific gravity bottle Explanation

Explanation

b: Graduated cylinder Explanation

Explanation

c: Pipette Explanation

Explanation

d: Burette Explanation

Explanation

3. The solvent used in the experiment should be:

a: One in which the powder is soluble Explanation

Explanation

b: One in which the powder is insoluble Explanation

Explanation

c: A volatile solvent only Explanation

Explanation

d: A mixture of solvents Explanation

Explanation

4. Entrapped air bubbles during the experiment will:

a: Have no effect on result Explanation

Explanation

b: Increase true density value Explanation

Explanation

c: Cause errors by increasing apparent volume Explanation

Explanation

d: Decrease mass of displaced liquid Explanation

Explanation

5. The true density (ρₜ) is calculated using the formula:

a: ρₜ = Volume of powder / Weight of powder Explanation

Explanation

b: ρₜ = Weight of powder / Volume of liquid displaced by powder Explanation

Explanation

c: ρₜ = Volume of liquid / Weight of bottle Explanation

Explanation

d: ρₜ = (W₂ – W₁) / (W₄ – W₃) Explanation

Explanation

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