Virtual Labs

Determination of minimal inhibitory concentration (MIC) of an antibiotic

1. What does MIC stand for in microbiology?

a: Microbial Inhibition Concentration Explanation

Explanation

b: Minimal Inhibition Capability Explanation

Explanation

c: Minimum Inhibitory Concentration Explanation

Explanation

d: Microorganism Inactivation Control Explanation

Explanation

2. Which of the following methods is commonly used to determine the minimal inhibitory concentration (MIC) of an antibiotic?

a: Polymerase chain reaction (PCR) Explanation

Explanation

b: Western blotting Explanation

Explanation

c: Disc diffusion test Explanation

Explanation

d: Broth dilution method Explanation

Explanation

3. The minimal inhibitory concentration (MIC) is typically expressed in

a: Grams per milliliter (g/mL) Explanation

Explanation

b: Units per milliliter (U/mL) Explanation

Explanation

c: Micrograms per milliliter (μg/mL) Explanation

Explanation

d: Milligrams per milliliter (mg/mL) Explanation

Explanation

4. Which of the following best describes the minimal inhibitory concentration (MIC) of an antibiotic?

a: The highest concentration of an antibiotic that kills all bacteria in a sample. Explanation

Explanation

b: The lowest concentration of an antibiotic that inhibits visible bacterial growth. Explanation

Explanation

c: The concentration of an antibiotic required to prevent bacterial resistance. Explanation

Explanation

d: The concentration of an antibiotic that exhibits side effects in the host. Explanation

Explanation

5. What is the purpose of determining the MIC of an antibiotic?

a: To assess the cost-effectiveness of the antibiotic Explanation

Explanation

b: To evaluate the pharmacokinetics of the antibiotic Explanation

Explanation

c: To guide appropriate dosage and treatment duration Explanation

Explanation

d: To measure the toxicity of the antibiotic Explanation

Explanation

6. Which method is NOT used to determine the MIC of an antibiotic?

a: Broth dilution method Explanation

Explanation

b: Antimicrobial gradient method Explanation

Explanation

c: Disk diffusion test Explanation

Explanation

d: Polymerase chain reaction (PCR) Explanation

Explanation

7. In the disk diffusion test, what does a larger zone of inhibition around the disk indicate?

a: Higher concentration of antibiotic needed Explanation

Explanation

b: Greater effectiveness of the antibiotic against the bacteria Explanation

Explanation

c: Presence of antibiotic resistance Explanation

Explanation

d: Ineffectiveness of the antibiotic Explanation

Explanation

8. Which of the following is a consequence of not using the correct antibiotic dose based on MIC?

a: Reduced side effects Explanation

Explanation

b: Decreased risk of resistance development Explanation

Explanation

c: Increased risk of antibiotic resistance Explanation

Explanation

d: Enhanced effectiveness of the antibiotic Explanation

Explanation

9. Which test uses antibiotic-impregnated disks to determine the effectiveness of an antibiotic?

a: Broth dilution method Explanation

Explanation

b: Antimicrobial gradient method Explanation

Explanation

c: Disk diffusion test Explanation

Explanation

d: MIC microdilution Explanation

Explanation

10. What is a potential consequence of using too low an antibiotic dose that is not based on MIC?

a: Increased bacterial susceptibility to the antibiotic Explanation

Explanation

b: Accelerated bacterial eradication Explanation

Explanation

c: Development of antibiotic resistance Explanation

Explanation

d: Decreased side effect Explanation

Explanation