Virtual Labs

Phylogenetic Tree Reconstruction Using the Fitch-Margoliash (FM) Algorithm

1. In the simulator, the initial step in the FM algorithm is to find the pair of taxa with

a: Longest distance Explanation

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b: Smallest distance Explanation

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c: Equal distance Explanation

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d: No distance Explanation

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2. The primary goal of the Fitch-Margoliash algorithm is

a: To find the shortest evolutionary path in the taxa Explanation

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b: To find the number of nodes in a tree Explanation

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c: To minimize the difference between observed and estimated distances Explanation

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d: To find common ancestors based on morphological similarities Explanation

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3. To run the simulator, the user must provide a single stretch of biological sequence as input data

a: True Explanation

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b: False Explanation

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4. Formula for Distance Matrix Calculation

a: d = (number of differences) / (compared sites) Explanation

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b: d = (compared sites) / (number of differences) Explanation

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c: d = (number of nucleotides)/ (differences in nucleotides) Explanation

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d: d= (number of nucleotides)/ (number of sequences) Explanation

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5. To run the simulator, the first step is to identify

a: Similar sequence Explanation

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b: Dissimilar sequence Explanation

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c: Closest pair Explanation

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d: Clustering Explanation

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6. Identify the correct steps in the FM algorithm

a: Distance matrix calculation, closest pair identification, branch length calculation, rearranging distance matrix, single node Explanation

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b: Closest pair identification, distance matrix calculation, rearranging distance matrix, branch length calculation, single node Explanation

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c: Distance matrix calculation, rearranging distance matrix, closest pair identification, branch length calculation, single node Explanation

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d: Closest pair identification, rearranging distance matrix, distance matrix calculation, branch length calculation, single node Explanation

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